Institute for Separation and Process Technology > Research > Downstream processing > Development of design methods for process development of thermal separation technology and down-stream processing

Development of design methods for process development of thermal separation technology and down-stream processing

A new topic of the ITVP is development of interpretation methods for the targeted litigation, such as groups of molecules, isomers, enantiomers, Diastereomere, SunFuel, Phytoextrakte, Plant Made Pharmaceuticals, peptides, proteins, monoclonal antibodies.

Growing economic pressure and increasing limitations of healthcare systems require extensive process improvements. The aim of this work is to realize new efficient design methods, processes and equipment to develop concepts that allow new products to effectively produce and optimize the existing potentials in the production of synthetic and biotechnological pharmaceuticals and fine chemicals.

The field of interest is as follows:

     1. Design, construction and commissioning

         a) Plant a mini-test and

         b) a micro-pilot Plant


     2. Efficient methods for process development and intensification of Down-stream Processing

         a) Plant a mini-test and

         b) a micro-pilot Plant


All the necessary basic operations of thermal separation technology and downstream processing, such as solid extraction, liquid-liquid extraction, distillation, adsorption, chromatography, ion exchange, selective and UF/DF membranes and crystallization/precipitation with filtration and drying/lyophilization will be investigated.

Mini-and Micro-Plant experimental facilities for various basic operations must be designed, manufactured, measured and modeled. Existing industrial contacts/collaborations in various fields allow for interdisciplinary cooperation.

 

Contact person: Dipl.-Ing. Jan Kristof Eggersglüß

 

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